Dimethyltryptamine and other hallucinogenic tryptamines exhibit substrate behavior at the serotonin uptake transporter and the vesicle monoamine transporter.
J Neural Transm (Vienna) September 12, 2009 DOI: 10.1007/s00702-009-0308-8
Summary
Ever wonder how certain hallucinogens impact the brain? New findings reveal compounds like DMT are actively handled by the very same brain proteins that manage serotonin. Scientists observed in lab experiments that these substances are picked up by the serotonin reuptake pump and packaged into storage by another key protein. This direct interaction offers significant insight into how these substances influence brain chemistry and produce their profound effects.
Abstract
Dimethyltryptamine and other hallucinogenic tryptamines exhibit substrate behavior at the serotonin uptake transporter and the vesicle monoamine transporter.