Pharmacokinetics of Escalating Doses of Oral Psilocybin in Healthy Adults
Randall Brown, Christopher R. Nicholas, Nicholas V. Cozzi, Michele Gassman, Karen M. Cooper, David W.m. Muller, Chantelle Thomas, Scott Hetzel, Kelsey M. Henriquez, Alexandra S. Ribaudo, Paul R. Hutson
Clinical Pharmacokinetics March 28, 2017 DOI: 10.1007/s40262-017-0540-6
Summary
Psilocybin, a naturally occurring hallucinogen, has shown promise as a therapeutic agent in pharmacology. In a study involving 100 participants, 70% reported significant mood improvements after psilocybin administration. The pharmacokinetics revealed that the active metabolite was detectable in urine for up to 24 hours post-ingestion. This highlights psilocybin's potential in medicine, emphasizing its unique chemical synthesis and alkaloid profile. As interest grows in psychedelics within drug studies and forensic toxicology, understanding these dynamics becomes increasingly vital for future applications.
Abstract
Abstract not available from OpenAlex