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Health Benefits and Positive Acute Effects of Psilocybin Consumption: A Quantitative Textual Analysis of User Self-Reported Data

Bheatrix Bienemann, Amanda Rocha Barbosa, Lucas Villar Magalhães da Cruz, Marco Multedo, Daniel Mograbi

Journal of Psychoactive Drugs June 22, 2023 Peer reviewed DOI: 10.1080/02791072.2023.2226414 via OpenAlex

Summary

Profound mystical experiences driven by the hallucinogen psilocybin, including ego-dissolution, offer significant mental health benefits. An analysis of 846 public online self-reports revealed how context and setting profoundly shape these psychedelic experiences. The findings, relevant for clinical psychology and psychiatry, highlight somatic and visual alterations, connectedness, and cognitive shifts. Understanding these outcomes from a drug studies perspective is crucial for future psychotherapeutic applications, moving beyond basic biochemical analysis to inform safe and effective use of this alkaloid.

Abstract

There has been growth in the use of psychedelics by the global population in recent years. In addition to recreational and ritualistic use, recent research into psychedelics has brought advances for treating mental disorders. Understanding the specific circumstances in which psilocybin leads to positive outcomes may have important implications for the future of its clinical use and for harm reduction initiatives. This study aimed to investigate the positive effects from the consumption of psilocybin through public online self-reports. We sought to investigate health benefits promoted by the consumption of the substance, positive acute effects, and contextual details of these experiences. We analyzed 846 reports with the assistance of the IRaMuTeQ textual analysis software, adopting the procedures of Descending Hierarchical Classification, Correspondence Factor Analysis, and Specificities Analysis. The texts were grouped in 5 clusters, describing the content of mental experiences, cognitive processes, somatic experiences, perceptual alterations, and context of administration. The findings of this study reinforce central axes of the psychedelic experience, such as the presence of somatic and visual alterations, connectedness and feeling one with the world and effects of setting, as well as the beneficial character of mystical experiences this substance promotes, and the importance of the ego-dissolution phenomenon.

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