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Potencjał terapeutyczny wybranych substancji psychoaktywnych — przegląd najnowszych badań

Anna Stankiewicz, Jan Szewczyk, Julia Truszkowska, Stefan Modzelewski, Napoleon Waszkiewicz

Psychiatria June 5, 2024 Peer reviewed DOI: 10.5603/psych.99558 via OpenAlex

Summary

Psychedelics such as LSD, MDMA, psilocybin, and THC show therapeutic potential for treating various mental health disorders, including addiction, depression, anxiety, PTSD, and eating disorders. Recent research since 2019 also explored less common substances like 5-MeO-DMT and ibogaine. With the development of proper protocols, these psychoactive agents may become integral to effective treatment strategies.

Study at a glance

Key finding Psychedelics have shown therapeutic potential for a range of mental disorders.

Abstract

Drug therapies for many psychiatric conditions do not meet patients’ expectations. New agents are being sought to treat depression and anxiety disorders, among others. Scientific interest in psychoactive substances has increased over the past few decades. Recent studies provide evidence that psychedelics may find use in the treatment of a range of mental disorders. This paper describes new research conducted since 2019 on the most popular psychedelics: LSD, MDMA, psylocybin and THC. The analysis was expanded to include substances less popular in recreational and scientific use, such as 5-MeO-DMT, dextromethorphan, DMT, ibogaine, ketamine and mescaline. It appears that the hallucinogens described show therapeutic potential in the treatment of addiction (nicotine, alcohol and substance dependence), depression, anxiety (including anxiety concurrent in autism spectrum disorder), PTSD and eating disorders. Once appropriate protocols are developed, psychoactive agents may become a component of comprehensive and effective therapy.

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