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When formulation procedures strongly matter: a case study of ayahuasca use in Centro Luz Divina, Piedade, São Paulo, Brazil

Arilton Martins Fonseca, Eliana Rodrigues

Revista de Ciências Farmacêutica Básica e Aplicadas - RCFBA January 1, 2021 Peer reviewed DOI: 10.4322/2179-443x.0720 via OpenAlex

Summary

The study describes the history and methods of the Centro Luz Divina (CLD) in São Paulo, which produces various ayahuasca recipes. Interviews with ten leaders revealed that the center, established in 2002, uses plants like Psychotria viridis and Banisteriopsis caapi to create beverages with differing potencies. The two main recipes discussed, 'First Degree' and 'Second Degree', vary in preparation and plant concentration, potentially affecting their pharmacological properties. Future studies should consider these variations for therapeutic research.

Study at a glance

Design qualitative study
Sample size 10
Population leaders and priests from the Centro Luz Divina in São Paulo
Key finding Ayahuasca recipes produced at the CLD may have different potencies based on their preparation methods and plant concentrations.

Abstract

Objectives: The objectives of this study were (a) to describe the history of the formation of the Centro Luz Divina (CLD), Piedade, São Paulo, (b) to describe the plants and recipes involved in making ayahuasca, and (c) to provide information for future chemical and pharmacological studies of ayahuasca. Methods: During the 578 hours of fieldwork between 2017 and 2019, 10 interviewees were interviewed (two priests and eight CLD leaders). The methods and techniques from cultural anthropology were used to conduct a snowball sampling to select respondents and record data through unstructured interviews, participant observation and field diaries. Data on the history of the CLD’s formation, plants and beverage recipes were recorded. The plants were dry collected and deposited at the UNIFESP Herbarium. Results: The history of the formation of the CLD, which was founded in 2002, was detailed. This center produces several recipes of the ayahuasca beverage during rituals named feitios in Portuguese by using the plants Psychotria viridis and Banisteriopsis caapi. The process of making two of these recipes was detailed in the present study, and they are the “First Degree beverage” and “Second Degree beverage”, which vary in preparation time, concentration, diversity and amount of the plant used and may lead to different “potencies of the beverage”, according to the interviewees' reports. From a pharmacological point of view, higher degree beverages are probably richer beverages from the chemical and pharmacological perspectives. Conclusion: Ayahuasca recipes produced at the CLD may have different “potencies”. However, future chemical and pharmacological investigations should consider these and other types of ayahuasca found in other Daimist centers in their protocols since many studies suggest the use of the substances in this beverage for treating Parkinson’s, anxiety, depression, and other ailments, as described in the scientific literature.

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