The Role of Psilocybin in End-of-Life Care: Evidence, Mechanisms, and Guidelines
Mackenzie Unsworth, Mary Lou Galantino, Robert Sandoval
Oncology Rehabilitation in Practice November 1, 2025 Peer reviewed DOI: 10.26890/hntj1494
Summary
The article reviews the evidence and mechanisms behind psilocybin use in end-of-life care and offers guidelines for clinicians on assessing patient use and integrating psilocybin into clinical practice, considering its current legal status.
Abstract
This article aims to provide a brief overview of the evidence and mechanisms for psilocybin use in EOL care. Additionally, this article will provide guidelines for clinicians to assess patient use and integrate psilocybin into their clinical practice with respect to its current legal status.