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Lysergic acid diethylamide reverses aging- and neurodegeneration-associated brain transcriptional programs

bioRxiv May 29, 2026 Peer reviewed DOI: 10.64898/2026.05.26.727809

Summary

Lysergic acid diethylamide (LSD) has the potential to reverse brain transcriptional programs associated with aging and neurodegeneration. This suggests that LSD may play a role in addressing age-related cognitive decline and neurodegenerative diseases by altering gene expression in the brain.

Study at a glance

Key finding LSD reverses brain transcriptional programs linked to aging and neurodegeneration.

Abstract

Lysergic acid diethylamide reverses aging- and neurodegeneration-associated brain transcriptional programs

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