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LSD (Lysergic Acid Diethylamide)

Jayalakshmi Krishnan

Drug Addiction Mechanisms in the Brain April 8, 2024 Peer reviewed DOI: 10.2174/9789815223828124010005

Summary

LSD is a powerful hallucinogen that alters perception, mood, and sense of time. It can cause both pleasurable experiences and negative effects like paranoia or psychosis. LSD is derived from ergot, a fungus, and is commonly found in various forms such as blotter paper and tablets. There are no specific medications to treat LSD effects, but options like talk therapy and consultation with healthcare professionals are available.

Study at a glance

Key finding LSD can lead to both pleasurable and unpleasant experiences, including paranoia or psychosis.

Abstract

LSD is a potent hallucinogen. It was first synthesised in 1938. It is marketed under numerous names. Ergot, a fungus that develops on rye and grains, is used to make LSD. The effect of LSD is mind-altering, pleasurable, and stimulating. Sometimes, exposure to this drug causes so-called unpleasant experiences, such as “bad trips”. It is classified as a Class 1 drug (highly abused) by the Drug Enforcement Agency. Paranoia or psychosis can occur as a negative sequence of taking LSD. Changes in perception, sense of time and space, and mood are reported due to the use of LSD. This medication can be taken orally or through the tongue using tablets, droplets, or blotter paper. LSD is marketed in the streets as blotter paper, thin squares of gelatin, tablet form, liquid sugar cubes, and pure liquid form. Since this is a mindaltering drug, it causes changes in serotonin levels in the brain. LSD affects one's ability to make rational decisions. Speaking with a healthcare professional, talk therapy, and additional medical therapy are options since there is no medication to treat LSD.

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