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Drugs for anxiety: from chloral hydrate to novel therapeutics

Peter M. Haddad

The British Journal of Psychiatry May 28, 2026 Peer reviewed DOI: 10.1192/bjp.2026.10598 via OpenAlex

Summary

Anxiety disorders are prevalent and can significantly impair daily functioning. Current treatments have limited effectiveness and side effects, with little innovation in the field. The editorial reviews various anxiolytic therapies, including emerging psychedelic-assisted treatments, and emphasizes the urgent need for better medications to enhance quality of life for those affected.

Study at a glance

Key finding There is a major need for improved medications to reduce disability and improve quality of life for individuals with anxiety disorders.

Abstract

Anxiety disorders are common and disabling. Current drugs have limited efficacy, notable side-effects and little innovation. This editorial briefly reviews past, current and emerging anxiolytic treatments, including psychedelic-assisted therapies, and highlights key themes. There remains a major need for improved medications to reduce disability and improve quality of life.

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