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The Ghosts of Psychedelic Science: Haunting and Moral Repair

Phoebe Friesen

Neuroethics December 29, 2025 Peer reviewed DOI: 10.1007/s12152-025-09622-4 via Springer Nature

Summary

The field of psychedelic science is influenced by a troubling history marked by colonial harms, unethical research practices, and the impacts of the War on Drugs, which disproportionately affect racialized communities. These historical 'ghosts' highlight moral demands for acknowledgment, accountability, and potential reconciliation. The manuscript questions whether true reconciliation in psychedelic science can be achieved or if the field should continue to acknowledge its haunted past.

Study at a glance

Key finding The manuscript explores how historical injustices and ethical violations in psychedelic science create moral demands for acknowledgment and accountability.

Abstract

Psychedelic science is haunted. A dark past, and contemporary violations, litter the field with ghosts of appropriation, abuse, and a violent war on drugs. Yet, these forms of haunting often remain unseen in discussions of the ethical aspects of psychedelic science. This manuscript explores various ways in which ghosts populate our collective and individual set and settings when it comes to psychedelic drugs, and what moral demands these ghosts might place on us. The first section examines three forms of haunting in psychedelic science. Colonial harms loom large, as a booming psychedelic industry creates scars of appropriation, biopiracy, and ecological damage. In psychedelic research contexts, various harms to participants haunt the past and present, from unethical experiments funded by MK-Ultra to current concerns related to vulnerabilities and shortcomings within ongoing clinical trials. The War on Drugs has left further damage, preventing racialized communities from feeling safe in psychedelic contexts, given enduring effects of over-policing. The next section examines demands for moral repair that have been made in response to these ghost stories. These demands, which focus on themes of acknowledgement and accountability, compensation, and listening and learning, bear a striking resemblance to discussions of reconciliation in the wake of human rights abuses. In light of these demands, the final section asks whether reconciliation is either possible or desirable in psychedelic science, or if perhaps we’re better off remaining haunted.

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