In healthy adults, microdosing of LSD produced transient effects on mood
The Brown University Psychopharmacology Update July 1, 2023 Peer reviewed DOI: 10.1002/pu.31033
Summary
Microdosing of LSD over a 6-week period improved mood on the days doses were taken in healthy adult men. However, no long-term improvements in mood or cognition were observed following the trial.
Study at a glance
| Design | randomized controlled trial |
|---|---|
| Population | healthy adult men |
| Key finding | Microdosing LSD improved mood during dose days, but did not lead to longer-term improvements. |
Abstract
A randomized trial involving healthy adult men has found that microdosing of lysergic acid diethylamide (LSD) over a 6‐week period resulted in improved effects on mood during dose days. No longer‐term improvements in mood or cognition were reported. Study results were published online March 28, 2023, in Biological Psychiatry.