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A short-acting psychedelic intervention for major depressive disorder: a phase IIa randomized placebo-controlled trial.

Nat Med February 16, 2026 Peer reviewed DOI: 10.1038/s41591-025-04154-z via PubMed Central

Summary

A phase IIa randomized placebo-controlled trial investigated a short-acting psychedelic intervention for individuals with major depressive disorder. The study aimed to assess the efficacy and safety of this treatment compared to a placebo, although specific results and outcomes are not provided in the abstract.

Study at a glance

Design randomized controlled trial
Population individuals with major depressive disorder

Abstract

A short-acting psychedelic intervention for major depressive disorder: a phase IIa randomized placebo-controlled trial.

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