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Uso da ayahuasca no tratamento da depressão

Robenilson Diniz Alves, Epifanio Fernandes da Silva, Maria Loyse da Silva Fernandes, José Jorde Canuto da Silva, Joezilda Sousa Silvestre

RCMOS - Revista Científica Multidisciplinar O Saber November 22, 2021 Peer reviewed DOI: 10.51473/rcmos.v1i11.2021.178

Summary

Ayahuasca tea, made from the Banisteriopsis caapi vine and Psycotria viridis leaves, shows promise in treating depression due to its bioactive compounds like Betacarboline and Dimethyltryptamine (DMT). While the research indicates a significant increase in serotonin levels, it also notes that the pharmacological effects are not consistently effective as a treatment. Further studies are needed to ensure safety and efficacy for broader therapeutic use.

Study at a glance

Design literature review
Key finding The study highlights a significant increase in serotonin but notes that ayahuasca does not consistently produce an effective pharmacological effect as a treatment for depression.

Abstract

Depression is a chronic psychiatric illness that causes deep sadness and a strong feeling of hopelessness. In this sense, new therapies are being approached. Ayahuasca tea is an example, a drink made from the vine of the Banisteriopsis caapi.and the leaves of Psycotria viridis often used in religious rituals such as santo-daime, and which has also been shown to be effective in the treatment of depression and other mental disorders. The study investigates findings about the use of the plant in the treatment of depression. The work starts from a literature review collected mainly by articles in Portuguese and English, aimed at an analysis of the pharmacological effects highlighted in trials and pre-clinical studies. The results provide a range of promising data on the use of drinking for the treatment of depression. Standing out for containing bioactive compounds such as Betacarboline and Dimethyltryptamine (DMT) that interact synergistically, causing changes in the perception of reality and emotions. The research revealed a significant increase in serotonin in the highly acquired, it did not express a constant and effective pharmacological effect as a therapeutic. The tests were very consistent, implying the need for more research into the proper interactions of ayahuasca, in order to guarantee the safety and efficacy and thus spread the treatment in the near future.

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