The Use of MDMA for PTSD

Summary

MDMA has shown special efficacy in treating PTSD that is resistant to conventional treatments. It works by releasing serotonin and reducing activity in the amygdala and hippocampus, which may help patients overcome emotional reliving of traumatic memories. Originally rediscovered in the 1970s for couples counseling, MDMA later became popular in the rave scene as ecstasy.

Study at a glance

Abstract

MDMA is a powerful empathogen that works by releasing 5-HT It was rediscovered in the 1970s as a useful drug to break down anger and hostility in couples counseling Later it started to be used in the “rave” scene and its name was changed to ecstasy Recently, trials have shown it to have special efficacy in the treatment of PTSD that has proved resistant to conventional treatments Brain imaging studies have shown MDMA to reduce activity in amygdala and hippocampus, which may explain how it helps patients overcome the emotional reliving of traumatic memories