Acute and chronic effects of MDMA on molecular mechanisms implicated in memory formation in rat hippocampus: surface expression of CaMKII and NMDA receptor subunits.
Pharmacol Biochem Behav September 9, 2005 Peer reviewed DOI: 10.1016/j.pbb.2005.07.020 via PubMed
Summary
The study investigates how both acute and chronic exposure to MDMA affects molecular mechanisms related to memory formation in the rat hippocampus, specifically focusing on the surface expression of CaMKII and NMDA receptor subunits. The findings suggest alterations in these molecular pathways due to MDMA exposure, which may have implications for understanding its impact on memory.
Study at a glance
| Population | rats |
|---|---|
| Key finding | MDMA exposure alters the surface expression of CaMKII and NMDA receptor subunits involved in memory formation. |
Abstract
Acute and chronic effects of MDMA on molecular mechanisms implicated in memory formation in rat hippocampus: surface expression of CaMKII and NMDA receptor subunits.