Acute ketamine treatment produces long-term anxiolytic effects despite increasing oxidative stress in female Wistar Kyoto rats
bioRxiv July 1, 2026 Peer reviewed DOI: 10.64898/2026.06.26.734907
Summary
Acute ketamine treatment leads to long-term reductions in anxiety for female Wistar Kyoto rats, even though it increases oxidative stress levels. This suggests that ketamine may have beneficial effects on anxiety despite potential negative impacts on oxidative stress.
Study at a glance
| Population | female Wistar Kyoto rats |
|---|---|
| Key finding | Acute ketamine treatment produces long-term anxiolytic effects despite increasing oxidative stress. |
Abstract
Acute ketamine treatment produces long-term anxiolytic effects despite increasing oxidative stress in female Wistar Kyoto rats