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Rapid clinical improvement after intravenous ketamine in an adolescent with treatment-resistant depression, severe obesity, and pseudo-Cushing syndrome: A case report.

Asian J Psychiatr June 28, 2026 Peer reviewed DOI: 10.1016/j.ajp.2026.105077 via PubMed

Summary

An adolescent with treatment-resistant depression, severe obesity, and pseudo-Cushing syndrome experienced rapid clinical improvement after receiving intravenous ketamine. The case highlights the potential effectiveness of ketamine in treating complex cases of depression.

Study at a glance

Design case study
Sample size 1
Population an adolescent with treatment-resistant depression, severe obesity, and pseudo-Cushing syndrome
Key finding The adolescent showed rapid clinical improvement following intravenous ketamine treatment.

Abstract

Rapid clinical improvement after intravenous ketamine in an adolescent with treatment-resistant depression, severe obesity, and pseudo-Cushing syndrome: A case report.

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