How ketamine helps to overcome depression
eLife December 12, 2014 Peer reviewed DOI: 10.7554/elife.05418
Summary
Genetically modified mice were used to explore how ketamine affects NMDA receptors in the brain, demonstrating its potential to alleviate depression symptoms. The findings highlight the mechanism by which ketamine may exert its antidepressant effects.
Study at a glance
| Population | genetically modified mice |
|---|---|
| Key finding | Ketamine can target NMDA receptors in the brain to reduce symptoms of depression. |
Abstract
Genetically modified mice shed new light on how ketamine can target NMDA receptors in the brain to reduce the symptoms of depression.