REDUCED PSYCHEDELIC EFFECTS OF KETAMINE INFUSION AFTER ELECTROCONVULSIVE THERAPY: A REPORT ON THREE CASES.
Emmanuel Kiiza Mwesiga, Alinaitwe Racheal, Janet Nakigudde, Seggane Musisi
preprint DOI: 10.31234/osf.io/9w5ub
Summary
Patients who had prior electroconvulsive therapy (ECT) experienced lower psychedelic effects after ketamine infusion compared to a patient without prior ECT. Specifically, the mean scores on all domains of the hallucinogen rating scale were lower for those who received ECT. Further research is necessary to confirm and understand this association.
Study at a glance
| Sample size | 3 |
|---|---|
| Population | patients receiving ketamine infusion, with some having prior electroconvulsive therapy |
| Key finding | Patients with prior electroconvulsive therapy had lower mean scores on the hallucinogen rating scale after ketamine infusion compared to a patient without prior ECT. |
Abstract
Psychedelic side effects of ketamine limit its use for the treatment of suicide ideations. Psychedelic effects after ketamine infusion were assessed in two patients received prior electroconvulsive therapy (ECT) and one who had not. Patients who received ECT prior to the infusion had lower mean scores on all domains of the hallucinogen rating scale compared to the patient who did not receive prior ECT. Confirming and understanding this association is needed through more rigorous research methods.