Brain functional network correlates and predictors of the perioperative antidepressant effect of esketamine in breast cancer patients: a double-blind randomized controlled trial using resting-state fMRI and graph theory.
Transl Psychiatry March 6, 2026 Peer reviewed DOI: 10.1038/s41398-026-03929-3 via PubMed Central
Summary
The study investigates how brain functional networks relate to and predict the antidepressant effects of esketamine in breast cancer patients during the perioperative period. Using resting-state fMRI and graph theory, it identifies specific network correlates that may serve as predictors for treatment outcomes.
Study at a glance
| Design | double-blind randomized controlled trial |
|---|---|
| Population | breast cancer patients |
Abstract
Brain functional network correlates and predictors of the perioperative antidepressant effect of esketamine in breast cancer patients: a double-blind randomized controlled trial using resting-state fMRI and graph theory.