Multiple peripheral inflammatory markers in adolescents with major depressive disorder treated with repeated esketamine infusions: results from a randomized controlled trial.
J Affect Disord February 23, 2026 Peer reviewed DOI: 10.1016/j.jad.2026.121488 via PubMed
Summary
Adolescents with major depressive disorder who received repeated esketamine infusions showed changes in multiple peripheral inflammatory markers. The study highlights the relationship between inflammation and depression treatment outcomes in this population, although specific results on the markers are not detailed in the abstract.
Study at a glance
| Design | randomized controlled trial |
|---|---|
| Population | adolescents with major depressive disorder |
| Key finding | Changes in multiple peripheral inflammatory markers were observed in adolescents treated with repeated esketamine infusions. |
Abstract
Multiple peripheral inflammatory markers in adolescents with major depressive disorder treated with repeated esketamine infusions: results from a randomized controlled trial.