ChemInform Abstract: Observations Concerning the Synthesis of Tryptamine Homologues and Branched Tryptamine Derivatives via the Borrowing Hydrogen Process: Synthesis of Psilocin, Bufotenin, and Serotonin.
Silvia Bartolucci, Michele Mari, Giovanni Di Gregorio, Giovanni Piersanti
ChemInform July 1, 2016 Peer reviewed DOI: 10.1002/chin.201633131
Summary
The study reports on a selective indole alkylation reaction using Ir-catalyzed borrowing hydrogen methodology with amino alcohols as nitrogen-containing electrophiles. This approach highlights the effectiveness of the method in facilitating this type of reaction.
Study at a glance
| Key finding | The selective indole alkylation reaction is effectively achieved using Ir-catalyzed borrowing hydrogen methodology with amino alcohols. |
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Abstract
AbstractThe selective indole alkylation reaction applying the Ir‐catalyzed‐borrowing hydrogen methodology and using amino alcohols (II), (V), (VII) as suitable nitrogen‐containing electrophiles is reported.