5-Iodo-2-aminoindan (5-IAI): chemistry, pharmacology, and toxicology of a research chemical producing MDMA-like effects.
Toxicology letters March 27, 2013 Peer reviewed DOI: 10.1016/j.toxlet.2013.01.008 via PubMed
Summary
5-iodo-2-aminoindan (5-IAI) was anticipated in the recreational drug market in 2010 and identified in products in the UK in 2011. This compound is a psychoactive derivative of 2-aminoindane and acts as a rigid analogue of p-iodoamphetamine, producing effects similar to MDMA. The paper aims to summarize its clinical, pharmacological, and toxicological information.
Study at a glance
| Key finding | 5-IAI produces MDMA-like effects and has been identified in recreational products. |
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Abstract
In 2010, an internet snapshot of EMCDDA anticipated the presence of 5-iodo-2-aminoindan (5-IAI) within the recreational drug market. In 2011, this compound, a psychoactive derivative of 2-aminoindane, was identified in recreational products sold in the United Kingdom. 5-IAI is a rigid analogue of p-iodoamphetamine producing MDMA-like effects. The aim of this paper is to summarize the clinical, pharmacological, and toxicological information about this new potential drug of abuse.