Aromatic Bromination Abolishes the Psychomotor Features and Pro-social Responses of MDMA ("Ecstasy") in Rats and Preserves Affinity for the Serotonin Transporter (SERT).
Front Pharmacol February 28, 2019 Peer reviewed DOI: 10.3389/fphar.2019.00157 via PubMed Central
Summary
Aromatic bromination of MDMA in rats eliminated psychomotor effects and pro-social responses typically associated with the drug, while still maintaining its affinity for the serotonin transporter. This suggests that bromination alters the behavioral impacts of MDMA without affecting its binding properties.
Study at a glance
| Population | rats |
|---|---|
| Key finding | Aromatic bromination of MDMA abolished its psychomotor features and pro-social responses in rats. |
Abstract
Aromatic Bromination Abolishes the Psychomotor Features and Pro-social Responses of MDMA ("Ecstasy") in Rats and Preserves Affinity for the Serotonin Transporter (SERT).