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Advancements in Treating Psychiatric Disorders With Psilocybin

David A. Gorelick

April 23, 2024 DOI: 10.64239/pi-qt6202

Summary

Psilocybin may be effective for treating treatment-resistant depression, providing rapid and lasting effects. However, its current use requires extensive psychotherapy, which could hinder accessibility and raise costs. The effectiveness of psilocybin alone, without psychotherapy, is unclear, and there are still unknown long-term safety risks associated with its use.

Study at a glance

Key finding The efficacy of psilocybin without concurrent psychotherapy is unknown.

Abstract

Psilocybin shows promise for treatment-resistant depression, with rapid onset and long-lasting effects. Psilocybin treatment currently involves extensive psychotherapy sessions, which may limit accessibility and increase costs. The efficacy of psilocybin without concurrent psychotherapy is unknown. Long-term safety risks of psilocybin treatment remain uncertain.

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