Neurovascular Architecture Of The Brain As A Limit Of Biological Reproducibility: From The Connectome And Vasculome To The Problem Of Consciousness Identity

Summary

The study explores the human brain as a complex neurovascular system where neuronal and vascular components work together. It highlights that consciousness relies on both neural connections and metabolic integration, introducing the idea of a neurovascular limit to consciousness. The research emphasizes that replicating the brain involves more than just copying neuronal connections, suggesting a new perspective on consciousness and personal identity.

Study at a glance

Abstract

This article examines the human brain as an integrated neurovascular architecture in which neuronal, vascular, glial, and metabolic components form a unified functional system. Drawing on contemporary findings in neuroscience, the study analyzes mechanisms of neurovascular coupling, the role of the blood–brain barrier, the glymphatic system, and the energetic foundations of cognitive processes. Particular attention is devoted to the concept of the vasculome as an additional level of brain organization complementing the traditional connectome framework. The paper discusses the limitations of current approaches to brain reconstruction and proposes the conceptual Biological Non-Reproducibility Principle for complex self-organizing systems. A hypothesis of a neurovascular limit of consciousness is introduced, suggesting that conscious experience depends not only on neural architecture but also on sustained energetic and metabolic integration. The findings indicate that reproducing the brain cannot be reduced to copying neuronal connections alone. The study offers a new perspective on the continuity of consciousness, personal identity, and the boundaries of future technological reconstruction of the human brain. Keywords: neurovascular architecture; neurovascular unit; vasculome; cerebral microcirculation; blood–brain barrier; glymphatic system; biological reproducibility; consciousness identity; brain bioengineering; philosophy of consciousness.

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