Exploring the World of Psychedelics: An Introduction

Summary

Psychedelics, including tryptamines like psilocybin and DMT, and phenethylamines such as MDMA, have a long history of therapeutic use across cultures. While many psychedelics are considered medically safe, some, like ibogaine and NBOMe compounds, pose medical risks that need more attention. The classification of psychedelics as 'novel therapeutic agents' is misleading given their historical context.

Study at a glance

Abstract

Psychedelics have been used therapeutically for thousands of years by various cultures, and the term "novel therapeutic agent" should not describe them. The classic psychedelics are mainly tryptamines (e.g., psilocybin, DMT, LSD) and phenethylamines (e.g., MDMA, mescaline, 2C-B), with tryptamines being more studied currently. While most psychedelics are medically safe, some like ibogaine and NBOMe compounds have associated medical risks that require further discussion.