Lysergic Acid Diethylamide: Effects on the Developing Mouse Lens
Science May 2, 1969 Peer reviewed DOI: 10.1126/science.164.3879.574
Abstract
High doses (5 × 10- 6 gram) of LSD-25 given to Swiss-Webster females on gestation days 6, 7, 8, or 9 caused a high incidence of anterior subcapsular lens abnormalities. Accompanying this, the lens epithelium was often hyperplastic, and the lens bow was widened posteriorly in a fashion similar to cataracts induced by x-radiation. Confirmation of this effect of LSD-25 was obtained by a (duplicate) experiment 1 year after the observations reported.