Ontogenesis of self-disorders in the schizophrenia spectrum: A phenomenological neuro-developmental model.
Michele Poletti, Andrea Raballo
Schizophrenia research October 1, 2024 Peer reviewed DOI: 10.1016/j.schres.2024.08.007 via PubMed
Summary
Basic Self-disorders capture the experiential aspects linked to vulnerability for schizophrenia spectrum disorders. They emerge before major diagnostic symptoms and are detectable in populations with familial risk. This paper proposes a two-stage phenomenological-developmental model examining early deficits in multisensory integration and their impact on the development of the Minimal Self in the first years of life, leading to later schizotaxic vulnerability and typical anomalies of subjectivity.
Study at a glance
| Design | theoretical or philosophical paper |
|---|---|
| Key finding | Early deficits in multisensory integration impact the ontogeny of the Minimal Self, contributing to schizotaxic vulnerability and later self-disorders in schizophrenia spectrum disorders. |
Abstract
The concept of basic Self-disorders (SD) captures the experiential aspects associated with vulnerability to schizophrenia spectrum disorders (SSD). SD emerge prior to, and constitute the underlying structure for, the emergence of major diagnostic symptoms, including positive psychotic ones. SD are also detectable in populations with familial risk for SSD. This paper proposes a two-stage phenomenological-developmental model, exploring the early deficit in multisensory integration and their impact on the ontogeny of the Minimal Self in the first years of life. It also examines subsequent emergence of schizotaxic vulnerability, which later manifests as typical anomalies of subjectivity, such as basic symptoms and self-disorders.