Synthesis of deuterium‐labelled standards of (±)‐DOM and (±)‐MMDA
Ajam C. Shaikh, Yu‐yun Wang, Chinpiao Chen
Journal of Labelled Compounds and Radiopharmaceuticals June 1, 2007 DOI: 10.1002/jlcr.1378
Summary
A method for synthesizing deuterium-labeled versions of two psychoactive amphetamine derivatives, DOM and MMDA, is described. The labeled compounds are intended for use as internal standards in gas chromatography–mass spectrometry (GC–MS) assays to improve measurement accuracy.
Study at a glance
| Characteristics | Method development Peer reviewed |
|---|---|
| Citations | 9 |
| Key finding | Deuterium-labeled DOM and MMDA were synthesized for potential use as internal standards in GC-MS assays. |
Abstract
AbstractThis study describes the synthesis of deuterium‐labelled (±)‐4‐methyl‐2,5‐dimethoxyamphetamine (DOM) and (±)‐1‐(7‐methoxy‐1,3‐benzodioxol‐5‐yl)propan‐2‐amine (MMDA). The isotopically labelled compounds are potentially used as internal standards in gas chromatography–mass spectrometry (GC–MS) assays. Copyright © 2007 John Wiley & Sons, Ltd.