The Age‐Well observational study on expert meditators in the Medit‐Ageing European project
Antoine Lutz, Olga Klimecki, Fabienne Collette, Géraldine Poisnel, Eider M. Arenaza‐Urquijo, Natalie L. Marchant, Vincent de la Sayette, Géraldine Rauchs, Eric Salmon, Patrik Vuilleumier, Eric Frison, Denis Vivien, Gaël Chételat
Alzheimer s & Dementia Translational Research & Clinical Interventions January 1, 2018 DOI: 10.1016/j.trci.2018.11.002 via OpenAlex
Summary
Long-term meditation expertise may protect against age-related decline. The Age-Well study compares 30 cognitively healthy older adults (65+) with at least 10,000 hours of mindfulness and compassion meditation to nonmeditator controls, using brain imaging, sleep, and biological measures sensitive to aging and Alzheimer's disease. Results are expected to clarify how meditation expertise affects aging and the mechanisms behind meditation-based interventions, informing future prevention trials for older populations.
Study at a glance
| Characteristics | Observational cross-sectional study Randomized Peer reviewed |
|---|---|
| Sample size | 30 |
| Population | Cognitively unimpaired individuals aged 65 years or older with at least 10,000 hours of practice in mindfulness meditation and loving-kindness and compassion meditation |
| Keywords | Observational study Ageing Gerontology Psychology Pathology |
| Citations | 18 |
| Key finding | Results are expected to foster understanding of the effects of meditation expertise on aging and of the mechanisms of action underlying meditation interventions. |
Abstract
INTRODUCTION: The Age-Well observational, cross-sectional study investigates the affective and cognitive mechanisms of meditation expertise with behavioral, neuroimaging, sleep, and biological measures sensitive to aging and Alzheimer's disease (AD). METHODS: Thirty cognitively unimpaired individuals aged 65 years or older with at least 10,000 hours of practice in mindfulness meditation (MM) and loving-kindness and compassion meditation (LKCM) are selected. The outcomes are the neuroimaging brain correlates of MM and LKCM and the assessments of long-term meditation practices on behavioral, neural, and biological measures as compared to nonmeditator older controls from the Age-Well randomized controlled trial. RESULTS: Recruitment and data collection began in late 2016 and will be completed by late 2019. DISCUSSION: Results are expected to foster the understanding of the effects of meditation expertise on aging and of the mechanisms of action underlying the meditation intervention in the Age-Well randomized controlled trial. These finding will contribute to the design of meditation-based prevention randomized controlled trials for the aged population and to the exploration of the possible long-time developmental trajectory of meditation training.