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Interactions between classic psychedelics and serotonergic antidepressants: Effects on the acute psychedelic subjective experience, well-being and depressive symptoms from a prospective survey study.

J Psychopharmacol January 27, 2024 DOI: 10.1177/02698811231224217

Summary

People taking antidepressants often worry about combining them with psychedelics. New findings show these combinations appear relatively safe, with psychedelics still providing positive effects. Survey data revealed that while antidepressants slightly reduced the intensity of psychedelic experiences, participants still reported significant improvements in well-being and depression symptoms.

Abstract

Interactions between classic psychedelics and serotonergic antidepressants: Effects on the acute psychedelic subjective experience, well-being and depressive symptoms from a prospective survey study.

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