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The structural diversity of psychedelic drug actions revealed.

Nat Commun March 19, 2025 DOI: 10.1038/s41467-025-57956-7

Summary

Different psychedelic compounds interact uniquely with brain receptors, leading to distinct therapeutic effects. New research maps how various psychedelics bind to serotonin receptors, revealing why some may be better for treating depression while others show promise for addiction. This breakthrough helps explain their diverse mental health benefits and could guide future drug development.

Abstract

The structural diversity of psychedelic drug actions revealed.

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