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How to account for hallucinations in the interpretation of the antidepressant effects of psychedelics: a translational framework.

Psychopharmacology (Berl) March 29, 2022 DOI: 10.1007/s00213-022-06106-8

Summary

Psychedelics' antidepressant effects may work through more than just hallucinations. New evidence suggests these compounds create lasting brain changes that improve mood independently of visual experiences. The research proposes that while hallucinations often occur alongside therapeutic benefits, they're not necessarily causing the antidepressant effects, pointing to separate biological mechanisms.

Abstract

How to account for hallucinations in the interpretation of the antidepressant effects of psychedelics: a translational framework.

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