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Psilocybin for the treatment of posttraumatic stress disorder: A magic to treat a harmony of illusions?

Rakesh Khanna

Journal of Indira Gandhi Institute Of Medical Sciences January 1, 2024 Peer reviewed DOI: 10.4103/jigims.jigims_60_23 via OpenAlex

Summary

The profound complexity of posttraumatic stress often creates an illusion of simple fixes. While psilocybin, a chemical synthesis from alkaloids, shows promise as a catalyst in psychotherapy, understanding its full psychological and psychiatric impact requires meticulous observation. Much like using a MAGIC (telescope) to study distant phenomena, integrating insights from Psychedelics and Drug Studies and Complementary and Alternative Medicine Studies is vital. This holistic view, emphasizing the psychotherapist's role, avoids quick chemical solutions for inherently complex problems.

Abstract

Abstract A review of the literature on posttraumatic stress disorder (PTSD) suggests it to be a complex disorder with many contributing factors. The concept of PTSD has continued to evolve over time. A diagnosis of PTSD may be hard to get right. Studies suggest a wide variation in its presentation and diagnostic stability. It is tempting to explore the possibility of using chemicals that could help shorten the process of reaching the unconscious mind that could lead to more rapid remission. This article aims to review limitations in seeing the effectiveness of psilocybin (magic mushroom)-assisted therapy for PTSD. Psilocybin is supposed to be just a catalyst for treatment, while psychotherapy is considered the mainstay of treatment. The therapy itself is to be nondirective, geared toward providing a sense of safety for the patient in a vulnerable state and allowing the person to direct the support while being in a chemically compromised state. We may repeatedly be falling into the trap of trying to find simple solutions to problems that are by their very nature quite complex. All interactions take place in a certain context, and their effect will depend on how they are taken up by the whole person/world system.

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