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Genetic influence of CYP2D6 on pharmacokinetics and acute subjective effects of LSD in a pooled analysis.

Sci Rep May 25, 2021 DOI: 10.1038/s41598-021-90343-y

Summary

Your genes shape how your body processes substances like LSD. Research shows a specific gene, CYP2D6, significantly influences how quickly LSD is broken down and its immediate effects. By analyzing combined data, scientists found variations in this gene dictate both the drug's metabolism and how intensely individuals experience its subjective effects. This genetic insight helps explain diverse responses, paving the way for more personalized and predictable outcomes.

Abstract

Genetic influence of CYP2D6 on pharmacokinetics and acute subjective effects of LSD in a pooled analysis.

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