5 results for "amputations"
Ketamine as primary anesthetic for upper limb trauma during war: a case series of 100 surgeries at Rafik Hariri University Hospital, Lebanon's National War Trauma Referral Center.
Future science OA – December 01, 2026
preprint
Summary
Following the Beirut pager explosions, trauma anesthesia at RHUH for 100 amputation surgeries dramatically improved with ketamine. Initially, opioid-based care led to 18 respiratory complications and 65% postoperative opioid use. After ketamine's introduction for mass casualty patients, pain scores dropped from 7.8 to 3.2, respiratory complications became zero, and only 5% required postoperative opioids. This opioid-sparing approach, crucial for conflict medicine, maintained stable blood pressure in 94% of patients, highlighting ketamine's effectiveness.
Abstract
The Beirut pager explosions on September 17, 2024 resulted in mass casualties with severe upper limb trauma admitted to Rafik Hariri University Hos...
A brief review of complex regional pain syndrome and current management.
Annals of medicine – December 01, 2024
Summary
Chronic pain that spreads beyond an initial injury affects 200,000 Americans yearly. Treatment options have expanded dramatically, combining traditional medications like gabapentin and ketamine with innovative therapies. Doctors now use precise diagnostic tools (Budapest criteria) to identify this condition early. Advanced treatments include spinal cord stimulation, nerve blocks, and botulinum toxin injections. While severe cases may require amputation, most patients improve with early intervention and antioxidant therapy.
Abstract
Complex regional pain syndrome (CRPS) is a debilitating chronic pain condition that, although exceedingly rare, carries a significant burden for th...
Case report: Ibogaine reduced severe neuropathic pain associated with a case of brachial plexus nerve root avulsion.
Frontiers in pain research (Lausanne, Switzerland) – January 01, 2023
Summary
Imagine decades of severe, intractable neuropathic pain from a brachial plexus nerve root avulsion caused by vehicular trauma. One patient found remarkable relief. This individual's chronic pain was successfully managed with ibogaine, whose effects, potentially involving its active metabolite noribogaine, significantly reduced the suffering. This case highlights a promising new approach to pain management.
Abstract
Brachial plexus nerve root avulsion results from complete separation of the nerve root from the spinal cord and is one of the most challenging type...
Relief from intractable phantom pain by combining psilocybin and mirror visual-feedback (MVF)
Neurocase – March 04, 2018
Summary
Psilocybin combined with mirror-visual-feedback completely eliminated phantom limb pain, a major advance in pain management. This physical medicine and rehabilitation breakthrough revealed the brain's phantom limb map: touching a volunteer's leg evoked organized sensations. An illusion of removing a "nail" fastener also relieved specific pain. These insights into psychology, imaging the phantom, action observation, and the placebo effect offer new medicine avenues within psychedelics and drug studies, informing body representation, even the forehead.
Abstract
AL's leg was amputated resulting in phantom-limb pain (PLP). (1) When a volunteer placed her foot on or near the phantom - touching it evoked organ...
Multiple Systemic and Ocular Malformations Associated With Maternal LSD Usage
Archives of Ophthalmology – October 01, 1974
Summary
A boy born with severe malformations, including anencephaly and syndactyly, highlights potential risks of prenatal substance exposure. His mother ingested lysergic acid diethylamide (LSD) before and during pregnancy. Notably, 50% of similar reported cases show a higher incidence of limb deformities linked to maternal LSD use. Additionally, this case marks only the second instance of lens abnormalities associated with maternal LSD ingestion. The findings underscore the importance of understanding the effects of drugs on fetal development during pregnancy.
Abstract
A boy was born with multiple malformations including anencephaly with ectopic placenta, absent left arm, cleft lip and palate, syndactyly, coloboma...