10 results for "multinomial logistic regression"
Psilocybin microdosing in the United States: Insights from a nationally representative survey
Addiction – March 08, 2026
Summary
Over 8.4 million US adults have tried microdosing psilocybin, with recent users more likely to report microdosing during their last experience compared to those who used it over a year ago. Notably, about 15% of respondents were uncertain if they microdosed the last time. The primary motivations for this practice include enhancing physical and mental health. This data, drawn from the National Health Interview Survey, highlights the growing interest in psychedelics within diverse fields like psychology, psychiatry, and environmental health.
Abstract
At least 8.4 million US adults have microdosed psilocybin in their lifetime. Those who have used psilocybin within the past year are more likely to...
Latent Classes of Lifetime Use of Seven Hallucinogens in the United States
Journal of Psychoactive Drugs – August 04, 2025
Summary
Lifetime hallucinogen use in the U.S. reveals distinct patterns among 17,977 individuals. A significant 46% used LSD/Psilocybin, while 16% used Psilocybin alone. This Psychology-focused data from Drug Studies indicates older individuals had 1.5-6.4 times higher odds of using LSD/Psilocybin. Non-White participants showed 1.7-3.2 times higher odds for Ecstasy use. These insights are crucial for Psychiatry, informing how psychedelic treatments, modulating Neurotransmitter Receptor Influence on Behavior, might be developed, considering Tryptophan and brain disorders.
Abstract
Interest in and use of hallucinogens appears to be growing in the United States, yet less is known about the use of multiple hallucinogens. The aim...
Risk communication about high-dose MDMA: Impact of a hypothetical drug alert on future MDMA use.
Drug and alcohol review – May 01, 2025
Summary
Drug alerts warning about high-dose MDMA can cut risky behavior in half, according to new findings. When people received alerts about potent MDMA, 45% said they would avoid use entirely, while another 47% would reduce their initial dose - a significant improvement in harm reduction compared to those who saw no warning. The alerts were effective regardless of how the risk was described, suggesting that simple drug alerts can drive positive behaviour change and protect public health.
Abstract
Despite high-dose 3,4-methylenedioxymethamphetamine (MDMA) drug alerts being distributed, no research has been conducted as to changes in use in re...
0391 Racial/Ethnic Differences in Psychedelic Use and Sleep Satisfaction: Preliminary Findings from the Herbal Heart Study
SLEEP – May 01, 2025
Summary
A surprising finding in psychology highlights a complex link between psychedelic use and sleep satisfaction. Among 200 young adults, particularly within the Hispanic/Latino ethnic group, consuming psychedelics was associated with significantly poorer sleep. For instance, 33.9% of Hispanic/Latino psychedelic users reported sleep dissatisfaction, compared to 17.2% of non-users. Psilocybin users in this group faced 9.2 times higher odds of dissatisfaction. This insight from drug studies informs future medicine, clinical psychology, and psychiatry, emphasizing tailored support for sleep health.
Abstract
Abstract Introduction Research on psychedelic use and sleep satisfaction remains unclear despite increased use. This study examines the psychedelic...
To Move or Not to Move: Factors of Mind-Body Practice Engagement in a Population-Based Study.
Journal of integrative and complementary medicine – April 01, 2025
Summary
Nearly 6% of U.S. adults engage in combined mind-body practices (MBPs), such as meditation, yoga, tai chi, and qigong. Higher educational attainment correlates with increased participation in all MBP types, while significant disparities exist among racial-ethnic groups. Individuals experiencing moderate to severe psychological distress are about twice as likely to practice combined-MBPs compared to those without distress. These findings highlight the potential of combined-MBPs to address mental and physical health needs, suggesting that healthcare providers should recommend them for patients facing psychological challenges.
Abstract
Background: Mind-body practices (MBPs), which include seated- (meditation) and movement-based practices (yoga, Tai Chi, qigong), have grown increas...
The Global Psychedelic Survey: Consumer characteristics, patterns of use, and access in primarily anglophone regions around the world.
The International journal on drug policy – August 01, 2024
Summary
A groundbreaking international survey reveals that personal growth, not recreation, is the primary motivation for psychedelic use across global regions. This comparative analysis of 6,379 adults from 85 countries found that psilocybin, LSD, and MDMA are the most commonly used substances. Usage patterns vary by region, with North Americans more likely to microdose and seek therapeutic benefits. Most users prefer legal, quality-controlled sources and practice infrequent, intentional use.
Abstract
Despite advancements in policies governing psychedelic substances globally, our understanding of real-world psychedelic use and its variations acro...
Psilocybin therapy for treatment resistant depression: prediction of clinical outcome by natural language processing
Psychopharmacology – August 22, 2023
Summary
Artificial intelligence can accurately predict who will respond to psilocybin treatment for mood disorders. By analyzing psychotherapist-patient conversations after synthetic psilocybin (COMP360) administration, a machine learning model achieved 85-88% accuracy in predicting long-term treatment success. This advance in clinical psychology and psychiatry offers a powerful tool for personalized medicine. It allows early identification within the patient population who benefit from psychedelics, optimizing care by understanding how neurotransmitter receptor influence on behavior manifests in therapy. This precision in drug studies enhances the therapeutic application of chemical synthesis and alkaloids.
Abstract
Abstract Rationale Therapeutic administration of psychedelics has shown significant potential in historical accounts and recent clinical trials in ...
Psilocybin Therapy for Treatment Resistant Depression: Prediction of Clinical Outcome by Natural Language Processing
OpenAlex – September 30, 2022
Summary
Predicting long-term mood improvement from psilocybin for major depressive episode is now 85-88% accurate. This breakthrough in clinical psychology utilizes artificial intelligence and machine learning, specifically logistic regression, to analyze patient-therapist dialogue from psychological support sessions. Focusing on COMP360, a synthetic psilocybin alkaloid, this advancement in medicine and psychedelics and drug studies offers personalized prognostication across the population. Such insights are vital for mental health research topics, optimizing care for individuals with severe depression.
Abstract
Background: Therapeutic administration of psychedelic drugs has shown significant potential in historical accounts and in recent clinical trials in...
Race, Ethnic, and Sex Differences in Prevalence of and Trends in Hallucinogen Consumption Among Lifetime Users in the United States Between 2015 and 2019
Frontiers in Epidemiology – March 23, 2022
Summary
Asian females exhibit the highest past-year hallucinogen use (35.06%), over twice that of White males/females. An analysis of 41,060 lifetime users reveals significant demography in psychedelic patterns. Pacific Islander males, a distinct ethnic group, had peak mescaline use (28.27%). Black, Asian, and Multiracial individuals had greater odds (1.20–2.06) of recent hallucinogen use than White people. Females generally had lower odds, except for MDMA. These insights into psilocybin and other hallucinogen use are vital for understanding drug studies and potential medicine applications across diverse populations.
Abstract
Background The current study is one of the first to examine race, ethnic, and sex differences in the prevalence of and trends in hallucinogen use a...
Recent national trends in Salvia divinorum use and substance-use disorders among recent and former Salvia divinorum users compared with nonusers.
Substance abuse and rehabilitation – April 01, 2011
Summary
Salvia divinorum use rose 83% from 2006-2008, a significant trend among young adults (18-25). Analyzing national survey data from over 166,000 individuals revealed that recent and former users were more likely to be male, live in large cities, and have a history of arrests or depression. Polydrug use emerged as the strongest predictor. Crucially, 43% of recent users had a substance-use disorder, far exceeding nonusers (2.5%). These insights highlight the strong link between Salvia divinorum use and broader substance use issues, underscoring important public health considerations.
Abstract
CONTEXT: Media and scientific reports have indicated an increase in recreational use of Salvia divinorum. Epidemiological data are lacking on the t...