Guidelines and standards for the study of death and recalled experiences of death––a multidisciplinary consensus statement and proposed future directions
Annals of the New York Academy of Sciences February 18, 2022 Sam Parnia, Stephen G. Post, Matthew T. Lee et al. 68 citations
Advances in stem cell research, neuroscience, and resuscitation science have enabled scientific insights into what happens to the human brain in relation to death. Brain cells are more resilient to anoxia than previously assumed, becoming irreversibly damaged over hours to days postmortem. Resuscitation science has restored life to millions after cardiac arrest, and survivors describe a universal set of recollections related to death. This review examines death, recalled experiences during cardiac arrest, post-intensive care syndrome, and related phenomena, discussing potential mechanisms, ethical implications, and methodological considerations. It also addresses controversies in studying consciousness and recalled experiences of cardiac arrest and death in comatose subjects to standardize future research.