Preventing misidentification of 25I-NBOH as 2C-I on routine GC–MS analyses
Forensic Toxicology July 1, 2017 José Coelho Neto, Ana Flávia B. Andrade, Rogério Araújo Lordeiro et al.
25I-NBOH, a novel psychoactive substance found on blotter paper in Brazil, can be misidentified as 2C-I by routine gas chromatography–mass spectrometry (GC–MS) because it degrades into 2C-I inside the injector unless a derivatization procedure is used. A slight adjustment to the standard GC–MS method—shortening the solvent delay window—enables detection of an additional early chromatographic peak from the degradation, allowing distinction between 25I-NBOH and 2C-I without derivatization and preventing misidentification.