Presentation and Short-term Course of New Onset Cannabis Induced Psychotic Disorder in Males
medRxiv January 31, 2022 Deepak Cyril D’souza, Justin Raj, Suhas Ganesh et al. preprint
Male patients with new-onset Cannabis Induced Psychotic Disorder (CIPD) present with less severe psychotic symptoms and show greater improvement in both psychosis and cognitive deficits over four weeks of hospitalization compared to patients with psychosis unrelated to cannabis. Among 16 CIPD patients followed after discharge, 10 relapsed into psychosis within six months after resuming cannabis use. The findings suggest CIPD has a distinct short-term course with better acute resolution, but relapse of cannabis use may lead to poorer long-term outcomes. The study did not include female patients.