Mode matters: exploring how modes of cannabis administration affect THC plasma concentrations and subjective effects
Journal of Cannabis Research May 23, 2025 Margy Y. Chen, Ashley Brooks-Russell, Angela D. Bryan et al.
Dabbing, a method of vaporizing cannabis concentrates, produces higher blood THC concentrations and stronger subjective drug effects than smoking flower products via joints or bongs, though the intense intoxication fades more quickly. Vaping also shows a rapid decline in subjective effects. These findings come from a secondary analysis of two quasi-experimental studies with 252 participants who used their own legal-market cannabis products in a naturalistic setting. The results highlight that the mode of administration substantially influences THC exposure and the experience of intoxication, and future research should account for these differences.