Psychiatric comorbidities in a young man with subacute myelopathy induced by abusive nitrous oxide consumption: a case report.
Substance abuse and rehabilitation January 1, 2016 Falk Mancke, Gintarė Kaklauskaitė, Jennifer Kollmer et al.
A 35-year-old man with MRI-confirmed subacute myelopathy from nitrous oxide (N2O) use also had cannabinoid and nicotine dependence and abused amphetamines, cocaine, LSD, and ketamine. A transient psychotic and depressive episode from synthetic cannabinoid abuse preceded these findings. The case highlights that N2O toxicity can cause irreversible neurological damage if untreated for months, making it essential to consider N2O in patients with substance use disorders who develop new neurological deficits.