Rational Design, Synthesis, and Characterization of a Solid Δ9-Tetrahydrocannabinol Nanoformulation Suitable for “Microdosing” Applications
Cannabis and Cannabinoid Research August 9, 2023 Abhinandan Banerjee, W. Hosie, Ana Carolina Terso Ventura et al.
A nanoemulsion of THC was created using a solvent displacement technique, yielding droplets of about 190 nm that remained colloidally stable for at least six weeks. The liquid nanoemulsion was converted into a solid powder that could be redispersed in water without phase separation, retaining its THC potency. This solid format is suited for microdosing, a practice that might separate THC's health benefits from its psychotropic effects.