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Aaron J Lacy

Department of Emergency Medicine (L. C. W., A. M. T., W. H. S., S. D., and J. H. H.), the Division of Allergy, Pulmonary, and Critical Care Medicine (M. W. S., J. D. C., A. L. K., P. T. B., J. C. J., and E. W. E.), Department of Medicine, the Vanderbilt Institute for Clinical and Translational Research (M. W. S., J. D. C., and W. H. S.), the Critical Illness, Brain Dysfunction, and Survivorship Center (A. L. K., P. T. B., J. C. J., E. W. E., and J. H. H.), the Department of Biostatistics (C. A. J., and G. W.), Vanderbilt University Medical Center; the Geriatric Research, Education, and Clinical Center (J. C. J., E. W. E., and J. H. H.), Tennessee Valley Healthcare Center, Nashville, TN; the Department of Emergency Medicine (A. J. L.), Washington University, St. Louis, MO; and the Department of Emergency Medicine (I. H. S.), University of Colorado School of Medicine, Aurora, CO.

1 paper in the library · 1 citation · publishing 2025

Papers

Association Between Receipt of Ketamine vs Etomidate for Emergency Tracheal Intubation and Symptoms of Posttraumatic Stress Disorder at 12 Months.

CHEST critical care June 1, 2025 Lucas C Wollenman, Austin M Tipold, Matthew W Semler et al. 1 citation

Among critically ill patients receiving mechanical ventilation, those given ketamine for emergency tracheal intubation had fewer posttraumatic stress disorder (PTSD) symptoms at 12 months than those given etomidate. PTSD symptoms were measured with the PCL-5 scale (0-80). The median score was 7 for the ketamine group and 14 for the etomidate group. Probable PTSD (score ≥31) occurred in 15.4% of ketamine patients versus 20.2% of etomidate patients. The analysis adjusted for age, race, sex, education, pre-existing depression or PTSD, comorbidities, illness severity, sepsis, and intubation location. These results suggest a protective association but require confirmation in a randomized trial.

DOI: 10.1016/j.chstcc.2025.100136 Full text Anxiety Depression Ketamine Emergent tracheal intubation +3