Presence of cholestasis and its impact on survival in SARS-CoV-2 associated acute respiratory distress syndrome.
Scientific reports October 8, 2024 Mathias Schneeweiss-Gleixner, Katharina Krenn, Mathias Petter et al. 3 citations
Among critically ill COVID-19 patients with acute respiratory distress syndrome, more than half developed cholestasis—a liver condition marked by elevated alkaline phosphatase. Cholestasis was linked to use of extracorporeal membrane oxygenation, ketamine, high inflammation, and greater disease severity. Patients with cholestasis had worse survival in the ICU and at six months, indicating it is a negative prognostic marker.