Use of Ketamine in Patients with Multifactorial Neuropathic Pain: A Systematic Review and Meta-Analysis.
Pharmaceuticals (Basel, Switzerland) September 3, 2024 Alejandro Bruna-Mejias, Vicente Baeza, Javiera Gamboa et al. 4 citations
A systematic review examined evidence for low doses of ketamine in treating neuropathic pain, a condition marked by burning, stabbing sensations, and heightened sensitivity. The review, which searched multiple databases, found that low-dose ketamine did not produce statistically significant improvements in pain reduction or functionality compared to placebo. Specific measures such as the total symptom score showed a difference, but the neuropathy impairment score and symptom checklist indicated no significant benefit. No specific dosages were identified that support the use of low-dose ketamine for neuropathic pain.