Abnormal resting-state functional connectivity of the right anterior cingulate cortex in chronic ketamine users and its correlation with cognitive impairments.
Asian journal of psychiatry December 1, 2024 Jun Zhong, Fengchun Wu, Huawang Wu et al. 1 citation
Chronic ketamine users show worse cognitive performance than healthy controls in visual learning, speed of processing, working memory, and overall cognition. Brain scans reveal stronger functional connectivity between the right anterior cingulate cortex and the right postcentral gyrus in users. This enhanced connectivity is positively linked to reasoning and problem-solving scores, suggesting it may serve as a compensatory mechanism for cognitive deficits. No significant relationship was found between this connectivity and characteristics of ketamine use.