What Chemsex does to the brain - neural correlates (ERP) regarding decision making, impulsivity and hypersexuality.
European archives of psychiatry and clinical neuroscience February 1, 2025 Johanna Schwarz, Marcus Gertzen, Andrea Rabenstein et al. 14 citations
Chemsex users—men who have sex with men who use substances like methamphetamine, GHB, mephedrone, or ketamine to enhance sex—show more depression, hypersexuality, and sexual risk behavior than non-users. Their brain activity during a decision-making task revealed reduced N2 responses in fronto-central regions, indicating impaired executive function and inhibitory control. P3 amplitudes did not differ between groups. These deficits may contribute to greater risk of drug abuse and hypersexuality, and understanding them could inform interventions to reduce harm and improve well-being.