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Vincent Cirimele

Laboratoire Toxlab, 7 rue Jacques Cartier, Paris 75018, France.

1 paper in the library · 5 citations · publishing 2024

Papers

2-Fluorodeschloroketamine consumption: About two deaths and a case of self-mutilation.

Journal of analytical toxicology June 11, 2024 Salomé Riess, Marjorie Chèze, Aurelie Muckensturm et al. 5 citations

2-Fluorodeschloroketamine (2-FDCK), a new psychoactive substance similar to ketamine, was detected and quantified in three forensic cases: one of self-mutilation and two deaths. In peripheral blood, concentrations ranged from 457 to 5885 µg/L across the cases, and the main metabolites nor-2-FDCK, dihydro-nor-2-FDCK, and dihydro-2-FDCK were also found. Hair analysis in the two fatal cases showed 2-FDCK at approximately 4149 and 79824 pg/mg. Deschloroketamine (DCK) was present in all biological fluids and hair, but in one case it appeared to result from 2-FDCK metabolism rather than separate ingestion, suggesting the first report of DCK as a metabolite of 2-FDCK in both fluids and hair.